Riehl melanosis - Riehl黑变病 https://en.wikipedia.org/wiki/Riehl_melanosis
https://en.wikipedia.org/wiki/Riehl_melanosis
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References Riehl Melanosis 32491369
 Riehl Melanosis 32491369 NIH
Riehl melanosis 通常稱為色素接觸性皮膚炎。這是一種由過敏引起的皮膚病,常因化妝品中的香料及其他成分而發作。雖屬於皮膚炎的一種,Riehl melanosis 仍會出現皮膚色素沉著變化,且刺激症狀較輕。此病在膚色較深的人群中較常見。近期研究評估了 mid‑fluence QSNY 1064‑nm 雷射治療對於改善 Riehl melanosis 相關深層色素沉著的效果。另一項研究則結合了 low‑fluence 1064‑nm Q‑switched Nd:YAG 雷射、氫醌乳膏 (hydroquinone cream) 以及口服氨甲環酸 (tranexamic acid),大多數患者的病情獲得顯著改善。
Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
 Research Advances in the Treatment of Riehl’s Melanosis 37168093
 Research Advances in the Treatment of Riehl’s Melanosis 37168093 NIH
Riehl's melanosis 是一種因接觸某些過敏原並暴露於陽光下而引起的皮膚疾病。它會導致皮膚快速且漸進地出現灰棕色色素沉著,嚴重影響患者的精神與身體健康。雖然 Riehl's melanosis 的確切原因尚未明確,但現有研究顯示與過敏原的暴露密切相關。治療方面,曾嘗試過傳統藥物與雷射療法,通常同時配合外用漂白劑。雷射療法,尤其是使用 Q‑switched Nd:YAG 激光,已顯示出對 Riehl's melanosis 有希望的療效。結合多種治療方式已取得積極成果。
Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.